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EB病毒可在B淋巴细胞中潜伏感染,干扰机体免疫功能,刺激细胞增生和转化,并致癌。EB病毒感染非常普遍,与其相关的疾病有传染性单核细胞增多症、噬血细胞综合征、慢性活动性EB病毒感染、X连锁淋巴组织增生性疾病、鼻咽癌及淋巴瘤等。EB病毒感染最常见及预后最好的疾病是传染性单核细胞增多症。
Abstract:Epstein-Barr virus (EBV) may establish a latent infection of B lymphocytes, interfering with immune regulation, stimulating cell proliferation and transformation and causing cancers. EBV infections are very common. The diseases related to EBV infections are infectious mononucleosis, hemophagocytic syndrome, chronic active EBV infection, X-linked lymph proliferative disease, nasopharyngeal carcinoma and lymphoma etc. Infectious mononucleosis is the most frequent clinical type related to EBV infection, with best prognosis.
[1]高建明,李小玲,李桂源.EB病毒DNA整合与细胞癌变[J].国际病理科学与临床杂志,2005,25(4):327-329.
[2]高田野葳.EB病毒感染与致癌[J].日本医学介绍,2006,27(4):162-164.
[3]周小鸽.EB病毒小RNA检测的临床病理学意义[J].中华病理学杂志,2006,35(6):321-323.
[4]Takakuwa T,Luo WJ,Ham MF,et al.Integration of Epstein-Barr virus into chromosome6q15of Burkitt lymphoma cell line(Raji)induces loss of BACH2expression[J].Am J Pathol,2004,164(3):967-974.
[5]段红梅,谢正德,申昆玲.EB病毒相关淋巴细胞增生性噬血综合征研究进展[J].临床儿科杂志,2005,23(7):427-433.
[6]王咏梅,曲熙波.EB病毒引起肝脏损害110例临床分析[J].传染病信息,2006,19(3):156-157.
[7]周志平,聂为民,赵敏.慢性活动性EB病毒感染转为淋巴瘤1例报道[J].传染病信息,2010,23(5):302-303.
[8]Straus SE.The chronic mononucleosis syndrome[J].J Infect Dis,1988,157(3):405-412.
[9]Okano M,Kawa K,Kimura H,et al.Proposed guidelines for diagnosing chronic active Epstein-Barr virus infection[J].Am J Hematol,2005,80(1):64-69.
[10]Ohga S,Sanefuji M,Ishimura M,et al.Epstein-Barr virus load in cerebrospinal fluid of patients with chronic active Epstein-Barr virus infection[J].Pediatr Infect Dis J,2008,27(11):1027-1030.
[11]Falco RP,Rizzatti EG,Saggioro FP,et al.Flow cytometry characterization of leukemic phase of nasal NK/T-cell lymphoma in tumor biopsies and peripheral blood[J].Haematologica,2007,92(2):24-25.
[12]Lin TF,Ferlic-Stark LL,Allen CE,et al.Rate of decline of ferritin in patients with hemophagocytic lymphohistiocytosis as a prognostic variable for mortality[J].Pediatr Blood Cancer,2011,56(1):154-155.
[13]Chung HJ,Park CJ,Lim JH,et al.Establishment of a reference interval for natural killer cell activity through flow cytometry and its clinical application in the diagnosis of hemophagocytic lymphohistiocytosis[J].Int J Lab Hematol,2010,32(2):239-247.
[14]李诗敏,朱雄增.结外鼻型NK/T细胞淋巴瘤的研究进展[J].中国癌症杂志,2006,16(12):1079-1082.
[15]林素暇,宗永生,林汉良,等.EB病毒LMP1对鼻咽癌中瘤细胞分化的影响肿瘤[J].肿瘤,2003,23(2):99-101.
[16]Sato E,Ohga S,Kuroda H,et al.Allogeneic hematopoietic stem cell transplantation for Epstein-Barr virus-associated T/natural killer-cell lymphoproliferative disease in Japan[J].Am J Hematol,2008,83(9):721-727.
[17]Li YX,Yao B,Jin J,et al.Radiotherapy as primary treatment for stage IE and IIE nasal natural killer/T-cell lymphoma[J].J Clin Oncol,2006,24(1):181-189.
基本信息:
DOI:
中图分类号:R363
引用信息:
[1]周志平,陈威巍,汤勃等.EB病毒感染及其相关性疾病[J].传染病信息,2013,26(01):57-60.
基金信息:
国家“十一五”科技重大专项(2008ZX10005-004)